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. Author manuscript; available in PMC: 2020 May 10.
Published in final edited form as: J Control Release. 2019 Mar 11;301:54–61. doi: 10.1016/j.jconrel.2019.03.008

Figure 3. Targeting of anti-ICAM-1/liposomes to the inflamed brain.

Figure 3.

Biodistribution of radiolabeled targeted-liposomes (anti-ICAM-1 or control IgG) 30 min after intravenous injection of control or TNFα-injured animals. (A) blood, (B) lungs, (C) brain. *** (p<0.001, IgG vs anti-ICAM-1), *(p<0.05, IgG vs anti-ICAM-1), # (p<0.05 Control vs TNFα), one-way ANOVA (Bonferroni post-hoc analysis) Mean±SD, n=3 (for IgG and control anti-ICAM-1), n=4 (TNFα, anti-ICAM-1).