Table 1. Nanocarriers characteristics.

Nanocarriers were measured by dynamic light scattering before and after binding the antibodies and before being injected into the animals. Antibodies: untargeted IgG as a control or anti-ICAM-1; polydispersity index: PDI.

Nanocarrier	Size (nm) M±SD, Z average Before conjugation, (PDI:M±SD)	n	Size (nm) M±SD, Z average After conjugation,(PDI:M±SD)	n
IgG-NPs	190 (Commercial), (<0,1)	NA	302.6±43.0, (0.13±0.08)	11
anti-ICAM-1-NPs	190 (Commercial), (<0,1)	NA	317.1±14.6, (0.12±0.03)	20
IgG-liposomes	108.2 ±4.8, (0.10±0.02)	16	134.6±11.1,,(0.16±0.02)	13
anti-ICAM-1-liposomes	108.2 ±4.8, (0.10±0.02)	16	147.5±33.8, (0.25±0.07)	16