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. 2019 May 3;10:409. doi: 10.3389/fgene.2019.00409

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Copyright © 2019 Yang, Zhou, Li, Liu, Zhang, Ao, Li and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Differential expression analysis of mRNAs and lncRNAs during porcine postnatal pineal development. (A,B) Heatmap showing the differentially expressed mRNAs (A) and lncRNAs (B) during porcine postnatal pineal development. (C) Experimental validation of RNA-seq data by RT-qPCR. Gene expression differences between developmental stages were evaluated based on the RNA-Seq data using the edgeR package. Error bars are SEM, n = 3. ^∗P < 0.05, ^∗∗P < 0.01, ^∗∗∗P < 0.001. (D) Venn diagram showing the number of differentially expressed mRNAs and lncRNAs between different development stages. (E–G) GO biological process analysis of the up-regulated and down-regulated genes between Y180-Y30 (E), Y300-Y30 (F), and Y300-Y180 (G).