Figure 1.

DLX6-AS1 is upregulated in PC tissues and cell lines.

Notes: (A) The mRNA expression of DLX6-AS1 in PC tissues and adjacent non-tumor tissues of 60 PC patients was determined by qRT-PCR. DLX6-AS1 was highly expressed in PC tissues. (B) Five-year survival rate of PC patients with high (n=28) and low (n=32) DLX6-AS1 expression was analyzed by Kaplan–Meier method and log-rank test. The patients with a low DLX6-AS1 expression level (less than or equal to median, n=32) presented better survival rates compared with those with a high DLX6-AS1 expression level (greater than or equal to median, n=28). (C) The mRNA expression level of DLX6-AS1 in normal HPDE cells and six PC cell lines (Panc-1, Bxpc-3, AsPC-1, Capan-1, CFPAC-1, and MIA PaCa-2) was determined by qRT-PCR. DLX6-AS1 expression was significantly higher in all the PC cell lines than HPDE cells. Data are presented as mean ± SD. ***P<0.001 vs HPDE cells.

Abbreviations: HPDE, human pancreatic ductal epithelial; PC, pancreatic cancer; qRT-PCR, quantitative reverse transcription PCR.