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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: J Mol Cell Cardiol. 2019 Feb 12;129:27–38. doi: 10.1016/j.yjmcc.2019.01.007

Fig. 2.

Fig. 2.

Loss of cardiac Med13 results in minimal alterations in cardiac function following 4 weeks of PTU. WT or Med13cKO mice were fed normal chow (NC) or a PTU diet for four weeks or a PTU diet for four weeks followed by T3 treatment at a dose of 1 μg/g body weight for three days (PTU + T3). A-B. Ratio of heart weight to body weight (HW/BW) or ejection fraction (EF) in mice of the indicated genotype in each group. n=3–19. Data are mean ± SEM. C. Whole heart hematoxylin and eosin (H&E) stain (top) or trichrome stain at 40x magnification (bottom) in mice of the indicated genotype that received either normal chow (NC) or a PTU diet (PTU). Statistics performed using Two-way ANOVA with Tukey’s multiple comparisons test.