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. Author manuscript; available in PMC: 2019 May 10.
Published in final edited form as: J Clin Cell Immunol. 2015 Jun 23;6(3):332. doi: 10.4172/2155-9899.1000332

Figure 7.

Figure 7

SAP inhibits IFN-α production triggered by DNA-containing amyloids. (A–C) PBMC were incubated with control (HSA+DNA) or DNA-amyloid with or without SAP (50 μg/ml) for 24 hrs. Supernatants were analyzed by ELISA for IFN-α (A), IL-6 (B) and TNFα (C) secretion. Error bars are means ± SEM of six donors. (D) Purified pDCs were incubated with control or DNA-amyloid, and IFN-α was quantified by ELISA after 24 hrs of culture. Error bars are means ± SEM of six donors (*p<0.05 and **p<0.005 compared with DNA-amyloid without SAP).