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. 2019 May 8;39(19):3611–3626. doi: 10.1523/JNEUROSCI.1392-18.2019

Figure 2.

Figure 2.

Maturation of glutamate uptake limits ambient glutamate after P7. a, Example recording, binned in 5 s increments, from a P7 L5P voltage-clamped at 40 mV during bath application of 100 μm TBOA. Gray dashed line indicates baseline. Black dashed line indicates holding current in TBOA at P14. Red dashed line indicates holding current in TBOA at P7. Calibration, 60 s. b, Capacitance-normalized, TBOA-induced holding currents binned by age (p < 7, n = 6 cells/3 animals; P7–P8, n = 7 cells/3 animals; P14+, n = 8 cells/4 animals). Circles represent individual cells. Lines indicate mean ± SEM. **p = 0.0080 (one-way ANOVA with Tukey post hoc test). ***p = 0.00082 (one-way ANOVA with Tukey post hoc test).