Figure 1.

The African American Cardiovascular Pharmacogenetic Consortium (ACCOuNT) Transdisciplinary Collaborative Center (TCC). Although both the discovery and translational projects are independent efforts, the overall interactions of these projects within ACCOuNT will help to develop a pipeline from which newly discovered single‐nucleotide polymorphisms (SNPs) in the Discovery Project and SNPs curated via PharmGKB will be investigated within the Translational Project. Data gathered within the Translational Project will inform which drugs are relevant candidates for investigation within the Discovery Project. Results of the Translational Project will be evaluated by the Implementation Advisory Council (IAC), which will collaborate with regional community partners for implementation planning and pilot project development. The ACCOuNT Data Commons will house information generated via the Discovery Project will become a resource for the greater PGx community for discovery and validation of African American findings. All efforts will have oversight of our Community and Stakeholder Advisory Board (CSAB) within the Consortium Core, which has launched community‐based pilot projects. All projects and cores are supported by the infrastructure within the Administrative Core, which provides the foundation of the TCC.