Table 2.

Select examples of resources available to investigators through established research networks and organizations across the globe

Resource	Region	Information link
Pediatric Trials Network	USA	www.pediatrictrials.org 52
Critical Path Institute‐Pediatric Trials Consortium		https://c-path.org/programs/ptc/ 53
Guidance from the FDA		https://www.fda.gov/ScienceResearch/SpecialTopics/PediatricTherapeuticsResearch/default.htm 54 https://www.fda.gov/downloads/drugs/guidances/ucm425885.pdf 55 https://www.fda.gov/downloads/drugs/guidances/ucm360507.pdf 56
EMA	Europe	https://www.ema.europa.eu/en/human-regulatory/research-development/paediatric-medicines/paediatric-clinical-trials 57
Canadian Institutes of Health Research‐Institute of Human Development, Child and Youth Health	Canada	http://www.cihr-irsc.gc.ca 58
World Health Organization‐International Clinical Trials Registry Platform	International	https://www.who.int/ictrp/child/en/ 59
Guidance from the International Conference on Harmonization		https://www.ich.org/fileadmin/Public_Web_Site/ICH_Products/Guidelines/Efficacy/E11/Step4/E11_Guideline.pdf 60 https://www.ich.org/fileadmin/Public_Web_Site/ICH_Products/Guidelines/Efficacy/E11/E11-R1EWG_Step4_Addendum_2017_0818.pdf 61

EMA, European Medicines Agency; FDA, US Food and Drug Administration.