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. 2019 May 6;14:3221–3234. doi: 10.2147/IJN.S203072

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© 2019 Wusiman et al.

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Antigen-specific CD4⁺/CD8⁺ T cell activation. (A) Effects of drugs on splenic lymphocyte proliferation. (B) Ratio of CD3⁺CD4⁺ to CD3⁺CD8⁺ splenocytes harvested from vaccinated mice re-stimulated with OVA. Mice (n=4) were immunized using different vaccine formulations. ^a–e Bars with different superscripts differed significantly (P<0.05).