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. Author manuscript; available in PMC: 2019 May 10.
Published in final edited form as: Am J Sports Med. 2018 Jun 21;46(9):2222–2231. doi: 10.1177/0363546518778789

Figure 1.

Figure 1.

The effect of injured tendons on glycolysis with or without treatment with dichloroacetate (DCA). Injured Achilles tendons were harvested 1 week (1W) or 4 weeks (4W) after the Achilles injury surgery. [U-13C]glucose (D-Glucose-13C6, 400 mg/kg) was peritoneally injected 1 hour before euthanasia without or with DCA treatment (100 mg/kg, daily intraperitoneal injections). The extracts from uninjured or injured tendons (n = 4) were used for measurement of 13C enrichment (M%E/) in (B) 13C-labeled glucose or metabolites: (C) GA-3P, (D) ribose-5P, (E) lactate, or (F) alanine—the metabolism of which is shown in panel A. Values are presented as mean ± 1 SD. *P < .05. M%E, molar percentage enrichment.