Table 2.

Patient Characteristics in Matched Cohort

Characteristics	Total (n=30)	Untreated (n=15)*	Treated (n=15)†	p value
Age, mo, median (IQR)	21 (6–48)	23 (3–48)	19 (7–48)	0.88
Sex, n (%)
Male	13 (43.3)	8 (53.3)	5 (33.3)	0.46
Female	17 (56.7)	7 (46.7)	10 (66.7)
Weight, kg, median (IQR)	10.9 (7.823)	11.1 (5.4–24)	10.7 (8–23)	0.86
Diagnosis, n (%)
Respiratory	17 (56.7)	9 (60)	8 (53.3)	0.71
Cardiovascular	4 (13.3)	2 (13.3)	2 (13.3)
Oncology	2 (6.7)	0 (0)	2 (13.3)
Neurology	4 (13.3)	3 (20)	1 (6.7)
Infectious	2 (6.7)	1 (6.7)	1 (6.7)
Other	1 (3.3)	0 (0)	1 (6.7)
PIM, median (IQR)	0.4 (0.3–1.8)	0.3 (0.1–1.7)	0.4 (0.3–2.1)	0.24
PCPC, n (%)
Normal	19 (63.3)	12 (80)	7 (46.7)	0.17
Mild	3 (10)	0 (0)	3 (20)
Moderate	6 (20)	2 (13.3)	4 (26.7)
Severe	2 (6.7)	1 (6.7)	1 (6.7)
Length of mechanical ventilation, median (IQR)	8 (5–14)	7 (4–9)	14 (5–24)	0.017
Days of delirium, median (IQR)	3 (3–7)	3 (2–3)	6 (3–12)	0.022
Length of stay, median (IQR)	19.5 (11–44)	16 (10–23)	34 (17–62)	0.029
Disposition, n (%)‡
Home	20 (69.0)	13 (92.9)	7 (46.7)	0.032
Rehab	6 (20.7)	1 (7.1)	5 (33.3)
Hospital transfer	1 (3.5)	0 (0)	1 (6.7)
Died	2 (6.9)	0 (0)	2 (13.3)
Psychiatric history, n (%)
No	26 (86.7)	13 (86.7)	13 (86.7)	1.0
Yes	4 (13.3)	2 (13.3)	2 (13.3)
CAPD, median (IQR)	16 (14–20)	15 (14–20)	16 (14–21)	0.77
Type of delirium, n (%)
Hyperactive	3 (10.0)	0 (0)	3 (20.0)	0.15
Hypoactive	7 (23.3)	5 (33.3)	2 (13.3)
Mixed	20 (66.7)	10 (66.7)	10 (66.7)

PCPC, Pediatric Cerebral Performance Category; PIM, Pediatric Index of Mortality

^* Patients with delirium not treated with antipsychotics.

^† Patients with delirium and treated with antipsychotic.

^‡ Frequency missing = 1 in untreated.