Table 1:
Comparison of patient characteristics based on whether the patient received a Normal Saline Bolus versus No Bolus in the Emergency Department
| Fluid Type* |
||||
|---|---|---|---|---|
| Variable | Total (N=400) | No Bolus (N = 137) | NS Bolus# (N = 261) | P-value** |
| Sex - Male | 185 (46%) | 65 (47%) | 119 (46%) | 0.731 |
| Age (years) | 13.8 (4.9) | 13.8 (4.9) | 13.8 (4.9) | 0.902 |
| Patient Weight (kg) | 47.4 (21.3) | 46.5 (19.7) | 47.9 (22.1) | 0.652 |
| Type of Sickle cell anemia | 0.051 | |||
| HbSS | 367 (92%) | 121 (88%) | 245 (94%) | |
| HbS Beta-Zero Thalassemia | 33 (8%) | 16 (12%) | 16 (6%) | |
| Vital Signs (from triage) | ||||
| Temperature (0C) | 37.0 (0.6) | 37.0 (0.5) | 37.1 (0.6) | 0.212 |
| Heart Rate (beats/minute) | 97.7 (18.3) | 94.9 (17.3) | 99.1 (18.8) | 0.052 |
| Systolic Blood Pressure (mmHg) | 118.4 (13.1) | 117.8 (12.7) | 118.8 (13.3) | 0.432 |
| Diastolic Blood Pressure (mmHg) | 68.3 (10.8) | 68.4 (11.2) | 68.3 (10.5) | 0.902 |
| Mean Arterial Pressure (mmHg) | 85.0 (10.2) | 84.8 (10.6) | 85.1 (9.9) | 0.582 |
| Oxygen saturation (%) | 97.6 (2.6) | 97.7 (2.7) | 97.6 (2.6) | 0.312 |
| Fever at home or in the ED | 74 (18.5%) | 18 (13%) | 56 (22%) | 0.04 |
| First pain score recorded | 8.0 (2.2) | 8.0 (2.1) | 8.0 (2.1) | 0.712 |
| Minutes from first ED encounter to IV placement | 56.7 (41.3) | 51.8 (40.1) | 59.2 (41.7) | 0.052 |
| IVF bolus received in the ED | 263 (66%) | - | - | - |
| IV opioids received in the ED | 365 (91%) | 115 (84%) | 249 (95%) | <.0011 |
| Intranasal Fentanyl received in the ED | 75 (18.8%) | 43 (31%) | 32 (12%) | <.0011 |
| Total parenteral morphine equivalents given in ED (mg/kg) | 0.2 (0.2) | 0.3 (0.3) | 0.2 (0.2) | 0.722 |
| Total parenteral morphine equivalents given in ED (mg/kg/hr) | 0.1 (0.6) | 0.1 (0.09) | 0.1 (0.04) | 0.142 |
| Oral opioids received in the ED | 98 (24.5%) | 48 (35.0%) | 50 (19.2%) | <.0011 |
1
Chi-squared test.
2
Kruskal-Wallis test.
3.
Missing disposition data on 3 patients from Bolus group.
#
Of 400 patients, N=263 were given an IVF bolus. N=1 received ½ NS bolus and N=1 received LR bolus, which were not included in the Bolus vs. No Bolus data analysis for the table.
*
All values are given in N (%) or Mean (SD) unless otherwise specified
**
All comparisons are between the Bolus and No Bolus groups