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. Author manuscript; available in PMC: 2020 May 10.
Published in final edited form as: ACS Infect Dis. 2019 Feb 4;5(5):769–777. doi: 10.1021/acsinfecdis.8b00290

Figure 9. Increased rate of assembly with B-21 in 0.5 M NaCl.

Figure 9.

(a) Change in the number of counts with B-21 concentration integrated over the 15 min of the resistive-pulse measurements (initial 1.5–16.5 min of assembly). B-21 affected the extent of HBV assembly more dramatically in 0.5 M NaCl compared to experiments in 1 M NaCl. With a molar ratio of 4:1 B-21 to Cp149 dimer, the extent of assembly increased by ~20-fold, (b) Increase in pulse frequency over the initial 1.5 – 16.5 min of the assembly reaction. Similar to the experiments at 1 M NaCl (Figure S2), the pulse frequency increased significantly over time with B-21.