Table 2:

Adverse events

	General Anesthesia N=3236	Operator Directed Sedation N=1188	p
Total	212 (6.6%)	41 (3.5%)	<0.001
30 day in-hospital mortality	0 (0%)	0 (0%)	1.00
Cardiac arrest	25 (0.8%)	2 (0.2%)	0.04
New arrhythmia	78 (2.4%)	15 (1.3%)	0.03
New heart valve regurgitation	2 (<0.1%)	0 (0%)	1.00
Tamponade	0 (0%)	1 (<0.1%)	0.60
Air embolus	0 (0%)	0 (0%)	1.00
Embolic stroke	3 (0.1%)	0 (0%)	0.69
Device malposition	1 (<0.1%)	0 (0%)	1.00
Device embolization	4 (0.1%)	2 (0.2%)	1.00
Airway event	NA	3 (0.3%)	NA
Initiation of dialysis	1 (<0.1%)	0 (0%)	1.00
New endotracheal intubation	30 (0.9%)	7 (0.6%)	0.36
Initiation of extracorporeal membrane oxygenation	9 (0.3%)	0 (0%)	0.15
Initiation of ventricular assist device	3 (0.1%)	1 (<0.1%)	1.00
Bleeding event	32 (1.0%)	11 (0.9%)	0.99
Unplanned cardiac/vascular/other surgery	7 (0.2%)	0 (0%)	0.24
Vascular complication	43 (1.3%)	4 (0.3%)	0.01
Repeat catheterization	7 (0.2%)	1 (<0.1%)	0.60
Other	13 (0.4%)	3 (0.3%)	0.65