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The structure and antiviral activity of novel HBV nucleocapsid assembly inhibitors
| Chemotype | Compound Name | Structure | EC50 (μM) | CC50 (μM) |
|---|---|---|---|---|
| I | Comp. 1 |  |
6.68 | >10 |
| II | Comp. 2 |  |
2.77 | >10 |
| III | Comp. 3 |  |
0.83 | >10 |
| IV | Comp. 4 |  |
0.85 | >10 |
| Comp. 5 |  |
1.47 | >10 | |
| V | Comp. 6 |  |
2.25 | >10 |
| VI | Comp. 7 |  |
2.25 | >10 |
| VII | BA-53038B |  |
3.32 | >100 |
EC50 was determined by dot blot hybridization assay. CC50 was determined by MTT assay.
