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The effect of BA-53038B on HBV capsid (HepG2 cells transiently transfected)
| Compound | EC50 (μM) | ||||
|---|---|---|---|---|---|
| HBV1.3 | HBV1.3/core-F97L | HBV1.3/core-V124A | HBV1.3/core-V124F | HBV1.3/core-V124W | |
| DVR23 | 0.37 ± 0.002 | 0.45 ± 0.06 | 1.61 ± 0.05 | 1.57 ± 0.15 | >10 |
| BA-53038B | 0.67 ± 0.17 | 2.18 ± 0.81 | 0.40 ± 0.13 | 0.32 ± 0.06 | >10 |
EC50 was determined by real-time PCR assay.
