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Classification of caspases according to the point of entry into the apoptosis cascade.
| Initiator caspases | Executioner caspases | Inflammatory caspases | |
|---|---|---|---|
| Extrinsic pathway | Intrinsic pathway | ||
| Caspase 8 Caspase 10 |
Caspase 2 ↑ Caspase 9 ↓ |
Caspase 3 ↓ Caspase 6 Caspase 7 |
Caspase 1 Caspase 4 Caspase 5 Caspase 12 |
↓ represents the caspases that are underexpressed in adult ACC, ↑ represents the overexpression caspases.
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