Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 May 10;9:7193. doi: 10.1038/s41598-019-43760-z

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Induction of cell cycle arrest and apoptosis by QS1189 in MCL cells. (a) MCL cells were treated with QS1189 for 24 h prior to cell cycle analysis by propidium iodide (PI) staining. The experiment was repeated in triplicate. (b) G2/M related protein expression was detected by immunoblotting. (c) MCL cells were treated with QS1189 for 24 h, and then harvested and stained with Annexin V–FITC and PI. The percentage of apoptosis was the sum of the early apoptosis and late apoptosis population. Results are shown as the mean ± standard deviation of three independent experiments. *P < 0.05; **P < 0.005 compared to the control group. (d) Cleaved PARP and caspase-3 levels were detected by immunoblotting.