Table 2.
Relationships of TREML4 polymorphisms with coronary artery lesion extension in CAD patients.
| Polymorphism | All | Extension of coronary artery lesion | p | ||||
|---|---|---|---|---|---|---|---|
| Without | Low | Intermediate | Major | ||||
| rs2803495 A/G | N = 136 | N = 33 | N = 39 | N = 40 | N = 22 | ||
| Genotypes, % | AA | 77.9 (106) | 78.8 (26) | 82.1 (32) | 75.6 (31) | 73.9 (17) | 0.813 |
| (Codominant) | AG | 20.6 (28) | 21.2 (7) | 17.9 (7) | 22.0 (9) | 21.7 (5) | |
| GG | 1.5 (2) | 0 | 0 | 2.4 (1) | 4.3 (1) | ||
| (Dominant) | AA | 77.9 (106) | 78.8 (26) | 82.1 (32) | 75.6 (31) | 73.9 (17) | 0.863 |
| AG + GG | 22.1 (30) | 21.2 (7) | 17.9 (7) | 24.4 (10) | 26.1 (6) | ||
| Alleles, % | A | 88.2 (134) | 89.4 | 91.0 | 86.6 | 84.8 | 0.702 |
| G | 11.8 (2) | 10.6 | 9.0 | 13.4 | 15.2 | ||
| rs2803496 C/T | N = 134 | N = 31 | N = 39 | N = 40 | N = 23 | ||
| Genotypes, % | TT | 76.9 (103) | 83.9 (26) | 71.8 (28) | 80.5 (33) | 69.6 (16) | 0.526 |
| (Codominant) | CT | 22.4 (30) | 16.1 (5) | 28.2 (11) | 17.1 (7) | 30.4 (7) | |
| CC | 0.7 (1) | 0 | 0 | 2.4 (1) | 0 | ||
| (Dominant) | TT | 76.9 (103) | 83.9 (26) | 71.8 (28) | 80.5 (33) | 69.6 (16) | 0.492 |
| CT + CC | 23.1 (31) | 16.1 (5) | 28.2 (11) | 19.5 (8) | 30.4 (7) | ||
| Alleles, % | T | 88.1 (133) | 91.9 | 85.9 | 89.0 | 84.8 | 0.620 |
| C | 11.9 (1) | 8.1 | 14.1 | 11.0 | 15.2 | ||
Numbers of subjects are indicated in parentheses. Frequencies were compared by the Chi-Square test. p-Values refer to comparisons among genotype frequencies of the different models and among allelic frequencies. For less than 10% of all samples, the genotype could not be determined. ‘Without’, Friesinger index 0; ‘Low’, Friesinger index 1–5; ‘Intermediate’, Friesinger index 6–10; ‘Major’, Friesinger index 11–15.