Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 May 10;9:7248. doi: 10.1038/s41598-019-43493-z

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

NPY-saporin lesion selectively reduces Y1R-ir in the dorsal horn. Y1R, CGRP, NK1, or IB4 immunostaining in the dorsal horn of naïve rats 14 days after intrathecal injection of (A,D,G,J) blank saporin or (B,E,H,K) 1000 ng NPY-saporin. NPY-saporin decreased (C) Y1R but did not change immunostaining in the dorsal horn of (F) CGRP, (I) NK1-R or (L) IB4 as compared to blank-saporin controls. Values are expressed as integrated density of staining in dorsal horn. ★P < 0.05 compared to blank-saporin. Data represent mean ± SEM. Scale bars: 100 µm.