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. 2019 May 10;9:7203. doi: 10.1038/s41598-019-43591-y

Figure 5.

Figure 5

HUVECs-derived ApoExos are enriched in A- and/or U-rich nucleotide sequences (a,b) ApoExos contain more AU-rich (a) and less GC-rich 3nt motifs (b). Whole RNA sequencing adaptor-trimmed reads with good quality were chopped in 3nt-long k-mers which were then quantified using JellyFish. (b) Bar chart showing ApoExos top enriched motifs. (b) Bar chart showing motifs depleted in ApoExos. (c) ApoExos whole RNA load contains more uracil. Single nucleotide usage was calculated from same reads as in (a,b). (Two-tailed unpaired T test, *p ≤ 0.05, **p ≤ 0.01, n = 2).