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. 2019 May 10;9:7258. doi: 10.1038/s41598-019-43700-x

Figure 3.

Figure 3

Different molecule classes affected by heparin. Classification of heparin-regulated genes coding for protein classes showed that most molecules were either (1) proteins associated with cell signaling including proteins with nucleic acid binding properties, receptors, signaling molecules and transcription factors (marked in red), (2) extracellular matrix proteins and proteins associated with cell adhesion (marked in violet) or (3) enzyme modulators, hydrolases and transferases, but also proteins with transporter functions (marked in yellow). The indicated color code depicts cell sources, respectively. Number of genes per molecule class and data point have been inserted. Red and blue arrows indicate up- and downregulation, respectively.