Table 3.

Primary outcome measures at baseline, week 24/posttreatment and 3-months follow-up

Measure	Mean (95% CI)a		Group difference in change score	P	Effect size (95% CI)b
	KONTAKT + standard care (n = 23)	Standard care (n = 27)
SRS-2 (parent)
Baseline	91.1 (80.7–101.6)	89.0 (79.3–98.6)
Posttreatment	74.3 (63.1–85.5)	91.3 (81.5–101.1)	− 19.2 (− 29.9 to − 8.5)	0.001	0.76 (0.18–1.34)
Follow-up	68.5 (57.2–79.8)	87.0 (77.1–96.9)	− 20.7 (− 31.7 to − 9.7)	0.0001	0.82 (0.24–1.40)
SRS-2 (teacher)
Baseline	68.9 (57.5–80.3)	72.9 (60.9–84.9)
Posttreatment	55.0 (39.0–71.1)	73.9 (61.1–86.7)	− 14.9 (− 34.5 to 5)	0.15	0.50 (− 0.06 to 1.06)
Follow-up	59.0 (44.6–73.3)	70.7 (56.9–84.5)	− 7.7 (− 26.8 to 11.8)	0.45	0.26 (− 0.30 to 0.82)

SRS-2 Social Responsiveness Scale 2nd Edition

^a Data are presented as raw mean scores at baseline and least squares mean values for week 24/posttreatment and 3 months follow-up with 95% CIs for each assessment point

^b Effect sizes were calculated by taking the difference in the least squares means at 24 week/posttreatment and follow-up dividing by the pooled standard deviation at baseline; positive effect sizes favor KONTAKT