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. 2018 Sep 25;29(3):1625–1634. doi: 10.1007/s00330-018-5725-3

Table 3.

Performance of clinico-radiological, CE-T1, T2, and CE-T1+T2 models, and nomogram

Model Performance AUC (95% CI) ACC SEN SPE p value Cut-off
Clinico-radiological Training set 0.846 (0.831–0.861) 0.763 0.765 0.761 1.25E-9 0.472
Test set 0.828 (0.812–0.844) 0.773 0.823 0.686 1.63E-8 0.472
CE-T1 Training set 0.852 (0.837–0.868) 0.753 0.851 0.660 2.33E-9 0.266
Test set 0.826 (0.804–0.844) 0.804 0.800 0.807 1.07E-7 0.266
T2 Training set 0.768 (0.748–0.787) 0.711 0.809 0.620 5.71E-6 -0.091
Test set 0.733 (0.712–0.754) 0.680 0.629 0.710 1.46E-4 -0.091
CE-T1+T2 Training set 0.869 (0.855–0.884) 0.753 0.851 0.660 3.80E-10 0.134
Test set 0.803 (0.784–0.821) 0.791 0.771 0.790 8.16E-7 0.134
Nomogram Training set
Test set
0.899 (0.887–0.911)
0.871 (0.857–0.885)
0.814
0.794
0.936
0.857
0.700
0.758
1.31E-11
1.51E-9
-0.732
-0.732

The best performance in the test cohort is indicated in bold font. The cutoff values were calculated using the xtile function in R

AUC area under the curve, ACC accuracy, SEN sensitivity, SPE specificity, CE-T1 contrast-enhanced T1 weighted MR image, T2 T2 weighted MR image