Fig. 2.

Imaging examples of animals with different degrees of diastolic dysfunction and healthy control animals. The first row displays the echocardiographic mitral valve inflow (A1, B1, C1–1) and the septal mitral valve annular velocities (A1, B1, C1–2). The second row shows the T1ρ maps (A2, B2, C2–1) and the corresponding bull’s-eye plots (A2, B2, C2–2). The third row shows mFI maps (A3, B3, C3–1) and the corresponding bull’s-eye plots (A3, B3, C3–2). The fourth row shows the extracellular volume fraction maps (A4, B4, C4–1) and the corresponding bull’s-eye plots (A4, B4, C4–2). Differences in fibrosis content among the three groups of monkeys were clearly indicated by three fibrosis imaging markers with different image contrasts