Table 2.
Postoperative complications according to the Clavien–Dindo classification
| Factors | All patients | Matched patients | ||||
|---|---|---|---|---|---|---|
| NAC | Surgery first | P | NAC | Surgery first | P | |
| (N = 39) | (N = 94) | (N = 39) | (N = 37) | |||
| Operative time (min) | ||||||
| Median (range) | 311 (99–590) | 279 (124–575) | 0.001 | 311 (99–590) | 265 (124–519) | 0.006 |
| Intraoperative bleeding (g) | ||||||
| Median (range) | 645 (5–2950) | 526 (35–3700) | 0.001 | 645 (5–2950) | 380 (100–3700) | 0.086 |
| Postoperative complications | ||||||
| Total (%) | 9 (23.1) | 38 (40.4) | 0.0567 | 9 (23.1) | 15 (40.5) | 0.101 |
| Grade 1 | 4 (10.3) | 17 (18.1) | 0.260 | 4 (10.3) | 2 (5.4) | 0.433 |
| Grade 2 | 2 (5.1) | 11 (11.7) | 0.245 | 2 (5.1) | 7 (18.9) | 0.063 |
| Grade 3 | 3 (7.7) | 7 (7.4) | 0.961 | 3 (7.7) | 6 (16.2) | 0.250 |
| Grade 4 | 0 (0.0) | 4 (4.3) | 0.191 | 0 (0.0) | 1 (2.8) | 0.301 |
| Complications of all grade, (%) | ||||||
| Anastomotic leakage | 1 (2.6) | 1 (1.1) | 0.518 | 1 (2.6) | 1 (2.7) | 0.970 |
| Pancreatic fistula | 6 (15.4) | 9 (9.6) | 0.335 | 5 (15.4) | 5 (13.5) | 0.929 |
| Anastomotic stricture | 0 (0.0) | 3 (3.2) | 0.259 | 0 (0.0) | 0 (0.0) | |
| Bowel obstruction | 0 (0.0) | 5 (5.3) | 0.142 | 0 (0.0) | 2 (5.4) | 0.141 |
| Intraabodominal abscess | 0 (0.0) | 2 (2.1) | 0.359 | 0 (0.0) | 1 (2.7) | 0.301 |
| Pneumonia | 0 (0.0) | 6 (6.4) | 0.106 | 0 (0.0) | 3 (8.1) | 0.067 |
| Cholecystitis | 0 (0.0) | 3 (3.2) | 0.259 | 0 (0.0) | 0 (0.0) | 1.000 |
| Others | 2 (5.1) | 10 (10.6) | 0.313 | 2 (5.1) | 1 (2.7) | 0.587 |
| Complications of grade 3–4 | ||||||
| Pancreatic fistula | 3 (7.7) | 6 (6.4) | 0.784 | 3 (7.7) | 2 (5.4) | 0.643 |
| Anastomotic stricture | 0 (0.0) | 1 (1.1) | 0.518 | 0 (0.0) | 0 (0.0) | 1.000 |
| Bowel obstruction | 0 (0.0) | 2 (2.1) | 0.364 | 0 (0.0) | 1 (2.7) | 0.301 |
| Pneumonia | 0 (0.0) | 2 (2.1) | 0.364 | 0 (0.0) | 0 (0.0) | 1.000 |
| Postoperative hospital stay (days) | ||||||
| Median (range) | 14 (9–57) | 15 (7–106) | 0.397 | 14 (9–57) | 14 (10–70) | 0.695 |
Gr, Grade; Clavien–Dindo Classification
aThe total does not add up because of overlapping elements