Table 1.

Metabolic parameters of male C57BL/6J mice received a low-fat diet (LFD), a high-fat diet (HFD) or a high-fat diet plus exercise training (HFD + EXE).

Metabolic parameters	LFD	HFD	LFD + EXE
Initial body weight (g)	20.5 ± 0.4	20.1 ± 0.4	20.3 ± 0.4
Final body weight (g)	26.0 ± 0.8	38.5 ± 1.2a	27.9 ± 0.4b
Body weight gain (g)	5.5 ± 0.4	18.4 ± 0.8a	7.6 ± 0.2a,b
Epididymal fat weight (g)	0.27 ± 0.03	2.04 ± 0.14a	0.55 ± 0.04b
Epididymal fat/body weight ratio (%)	1.00 ± 0.09	5.26 ± 0.23a	1.94 ± 0.11a,b
Subcutaneous fat weight (g)	0.24 ± 0.04	1.78 ± 0.16a	0.49 ± 0.04b
Subcutaneous fat/body weight ratio (%)	0.94 ± 0.15	4.63 ± 0.38a	1.78 ± 0.16b
Serum metabolites
TG (mmol/L)	0.36 ± 0.03	0.57 ± 0.06a	0.38 ± 0.03b
TC (mmol/L)	2.36 ± 0.08	3.40 ± 0.15a	2.84 ± 0.11a,b
LDL-C (mmol/L)	0.17 ± 0.02	0.27 ± 0.03a	0.19 ± 0.01b
HDL-C (mmol/L)	2.13 ± 0.14	2.55 ± 0.19	2.29 ± 0.17

Data are mean ± SEM. n = 10 per group.

^aP < 0.05 for difference from LFD; ^bP < 0.05 for difference from HFD.