Table 1.

PCR Primers and CRISPR-Guide RNA Oligo Sequences

PCR primers
mGAPDH	Forward	5’- TCAACAGCAACTCCCACTCTTCCA-3’
	Reverse	5’- ACCCTGTTGCTGTAGCCGTATTCA-3
mRegIIIγ	Forward	5’-ATGCTTCCCCGTATAACCATCA-3’
	Reverse	5’-ACTTCACCTTGCACCTGAGAA-3’
mβ-defensin-1	Forward	5’- CCAGATGGAGCCAGGTGTTG-3’
	Reverse	5’- AGCTGGAGCGGAGACAGAATCC-3’
mβ-defensin-3	Forward	5’- AAAGGAGGCAGATGCTGGAA-3’
	Reverse	5’- ACGGGATCTTGGTCTTCTCT-3’
mβ-defensin-4	Forward	5’- GCAGCCTTTACCCAAATTATC-3’
	Reverse	5’- ACAATTGCCAATCTGTCGAA-3
mIL33	Forward	5’-GCTGCGTCTGTTGACACATT-3’
	Reverse	5’-CACCTGGTCTTGCTCTTGGT-3’
mHIF-1α	Forward	5’-AGCTTCTGTTATGAGGCTCACC-3’
	Reverse	5’-TGACTTGATGTTCATCGTCCTC-3’
mST-2	Forward	5’-CATGGCATGATAAGGCACAC-3’
	Reverse	5’-GTAGAGCTTGCCATCGTTCC-3’
hGAPDH	Forward	5’- CAGGAGGCATTGCTGATGAT-3’
	Reverse	5’- GAAGGCTGGGGCTCATTT-3’
hRegIIIα	Forward	5’-TATGGCTCCCACTGCTATGCCT-3’
	Reverse	5’-TCTTCACCAGGGAGGACACGAA-3’
CRISPR-guide RNA oligo sequences
STAT3	Forward	5’ – CACCGCGATTACCTGCACTCGCTTC – 3’
	Reverse	5’ – AAACGAAGCGAGTGCAGGTAATCGC – 3’
mTOR	Forward	5’ – CACCGTGATACGAACTAGCTCGTTG– 3’
	Reverse	5’ – AAACCAACGAGCTAGTTCGTATCAC– 3’
MEK1	Forward	5’ – CACCGCTTGTGCTTCTCCCGAAGAT– 3’
	Reverse	5’ – AAACATCTTCGGGAGAAGCACAAGC– 3’
MEK2	Forward	5’ – CACCGATGATCTGGTTGCGCACGGC– 3’
	Reverse	5’ – AAACGCCGTGCGCAACCAGATCATC– 3’
REG3γ	Forward	5’ – CACCGTAGGGCTATGAACCCAACAG– 3’
	Reverse	5’ – AAACCTGTTGGGTTCATAGCCCTAC– 3’
IL33	Forward	5’ – CACCGTGATCAATGTTGACGACTC– 3’
	Reverse	5’ – AAACGAGTCGTCAACATTGATCAC– 3’
ST-2	Forward	5’ – CACCGTTGATGTACTCGACAGTACG– 3’
	Reverse	5’ – AAACCGTACTGTCGAGTACATCAAC– 3’

PCR, polymerase chain reaction.