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. 2019 May 7;12(7):871–878. doi: 10.1016/j.tranon.2019.04.007

Figure 1.

Figure 1

Response to olaparib is blunted in models of therapeutic-resistant CRPC. (A) Cell growth assays were used to test response to olaparib in MDVR, AbiR, and TaxR cells versus parental C4-2B cells using indicated doses of olaparib over a 72-hour period. IC50 values were calculated and are represented in the table. (B) Colony formation assays were used to test response to olaparib in TaxR cells versus parental C4-2B cells. Quantification of the assay is shown (right panel). Ola = olaparib, * = P value ≤ .05.