Table 1.
Comparison of Various Computational Approaches’ AUC Values through 5-Fold Cross-Validation
| Method | RWRMDA | HDMP | IMCMDA | RLSMDA | MIDP | SPM | NNMDA |
|---|---|---|---|---|---|---|---|
| Breast neoplasm | 0.785 | 0.801 | 0.812 | 0.832 | 0.838 | 0.932 | 0.968 |
| Hepatocellular carcinoma | 0.749 | 0.759 | 0.744 | 0.794 | 0.807 | 0.918 | 0.966 |
| Renal cell carcinoma | 0.815 | 0.833 | 0.793 | 0.839 | 0.862 | 0.901 | 0.912 |
| Squamous cell carcinoma | 0.819 | 0.820 | 0.837 | 0.849 | 0.870 | 0.899 | 0.924 |
| Colorectal neoplasm | 0.793 | 0.802 | 0.766 | 0.831 | 0.845 | 0.885 | 0.927 |
| Glioblastoma | 0.680 | 0.700 | 0.781 | 0.714 | 0.786 | 0.840 | 0.911 |
| Heart failure | 0.722 | 0.770 | 0.924 | 0.738 | 0.821 | 0.950 | 0.945 |
| Acute myeloid leukemia | 0.839 | 0.858 | 0.861 | 0.853 | 0.915 | 0.957 | 0.916 |
| Lung neoplasm | 0.827 | 0.835 | 0.841 | 0.855 | 0.876 | 0.892 | 0.943 |
| Melanoma | 0.784 | 0.790 | 0.761 | 0.807 | 0.837 | 0.951 | 0.949 |
| Ovarian neoplasm | 0.882 | 0.884 | 0.875 | 0.909 | 0.923 | 0.949 | 0.928 |
| Pancreatic neoplasm | 0.871 | 0.895 | 0.894 | 0.887 | 0.945 | 0.954 | 0.954 |
| Prostatic neoplasm | 0.823 | 0.854 | 0.775 | 0.841 | 0.882 | 0.928 | 0.936 |
| Stomach neoplasm | 0.779 | 0.787 | 0.783 | 0.797 | 0.821 | 0.859 | 0.955 |
| Urinary bladder neoplasm | 0.821 | 0.850 | 0.813 | 0.845 | 0.897 | 0.898 | 0.920 |
| Average AUC | 0.799 | 0.816 | 0.817 | 0.826 | 0.862 | 0.914 | 0.937 |