Table 3.
Multivariate analysis of the correlation between clinical and pathological variables and OS.
| Factor | Hazard | 95%CI | p value |
|---|---|---|---|
| Complete Resection | |||
| R0/complete | 1.000 | ||
| R1/2/incomplete | 2.354 | 1.289-4.297 | 0.005 |
| Smoking index | |||
| <400 | 1.000 | ||
| ≥400 | 2.524 | 1.323-4.814 | 0.005 |
| CD3 percentage | |||
| ≤6% | 1.000 | ||
| >6% | 0.505 | 0.288-0.884 | 0.017 |
| PD-L1 expression in TILs | |||
| <8% | 1.000 | ||
| ≥8% | 2.182 | 1.061-4.486 | 0.034 |
| PD-L1 expression in tumor cells | |||
| <50% | 1.000 | ||
| ≥50% | 5.296 | 1.454-19.28 | 0.011 |
| LNR | 0.004 | ||
| LNR=0 | 1.000 | ||
| LNR>0,≤0.214 | 4.920 | 1.636-14.793 | 0.005 |
| LNR>0.214 | 6.005 | 1.880-19.178 | 0.002 |
LNR= Ratio of metastatic lymph nodes.