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. 2019 Mar 12;92(11):519–533. doi: 10.1212/WNL.0000000000007099

Figure 3. Susceptibility-weighted imaging.

Figure 3

Persistent phase rims in a gadolinium-enhancing lesion in a patient with secondary progressive multiple sclerosis. Postcontrast T1-weighted images demonstrate gadolinium enhancement evolution from centrifugal to centripetal. A hypointense rim can be visualized on noncontrast phase images when the lesion enhances centripetally, and is persistent after enhancement resolution (months 3, 6, 12, 18) and on T2* weighted images (months 6, 12, 18). MPRAGE = magnetization-prepared rapid gradient echo. Reproduced with permission from Absinta M, Sati P, Schindler M, et al. Persistent 7-tesla phase rim predicts poor outcome in new multiple sclerosis patient lesions. J Clin Invest 2016;126:2597–2609.