Table 3.
Top 10 differentially expressed miRNA, between local and metastatic breast cancers, in discovery cohort
| Rank | miRNA | baseMean | log2FoldChange | lfcSE | stat | P value |
|---|---|---|---|---|---|---|
| 1 | hsa-miR-487a-5p | 10.204322 | −6.5949809 | 2.08622397 | −3.1612046 | 0.00157118 |
| 2 | hsa-miR-376c-3p | 9.66930256 | −6.2249402 | 2.16041009 | −2.8813697 | 0.00395951 |
| 3 | hsa-miR-181a-2-3p* | 10.0812243 | 6.10481296 | 2.17498667 | 2.80682775 | 0.0050032 |
| 4 | hsa-miR-6721-5p | 11.0766671 | −5.5985336 | 2.00252808 | −2.7957329 | 0.00517822 |
| 5 | hsa-miR-329-3p* | 40.6587497 | −4.2606132 | 1.5758723 | −2.7036539 | 0.00685817 |
| 6 | hsa-miR-665 | 4.33646293 | −5.5104353 | 2.17214494 | −2.5368635 | 0.01118505 |
| 7 | hsa-miR-331-3p* | 9.380562 | −4.2942354 | 1.79092278 | −2.3977781 | 0.01649485 |
| 8 | hsa-miR-4433a-5p | 15.8475709 | 3.90544954 | 1.65092455 | 2.36561359 | 0.01800022 |
| 9 | hsa-miR-2277-3p | 3.59270664 | −4.7490645 | 2.08789239 | −2.2745734 | 0.02293153 |
| 10 | hsa-miR-6734-5p | 25.3078788 | 3.92134038 | 1.73154349 | 2.26465024 | 0.02353415 |
*Selected miRNAs in bold