Table 4.
Correlations between clinical data and pathologic classifications by the updated Oxford classification or the International Study of Kidney Disease in Children classification
| MAP, mmHg | P value | Proteinuria, g/24 h | P value | eGFR, ml/min/1.73m2 | P value | Scr, μmol/L | P value | |
|---|---|---|---|---|---|---|---|---|
| International Study of Kidney Disease in Children classification | ||||||||
| ISKDC-G0 | 93.8 ± 10.7 | 0.75 (0.40, 1.75) | 123.8 (96.0, 145.4) | 60.0 (50.5, 75.0) | ||||
| ISKDC-G1 | 95.9 ± 10.6 | 1.50 (0.75, 3.00) a | 111.4 (81.4, 134.6) a | 68.0 (55.0, 91.5) a | ||||
| ISKDC-G2 | 95.0 ± 10.5 | 3.60 (2.00, 5.50)ab | 30.7 (24.5, 138.6)ab | 150.0 (56.0, 244.5)ab | ||||
| Updated Oxford classification | ||||||||
| Messangial proliferation | ||||||||
| M0 | 95.1 ± 10.4 | 0.303 | 1.23 (0.60, 3.00) | 0.859 | 116.2 (87.6, 139.6) | 0.429 | 65.0 (53.0, 81.3) | 0.098 |
| M1 | 94.3 ± 12.4 | 1.34 (0.73, 3.01) | 107.3 (85.5, 134.7) | 72.0 (56.0, 92.0) | ||||
| Endocapillary proliferation | ||||||||
| E0 | 94.5 ± 10.3 | 0.160 | 1.00 (0.46, 2.15) | < 0.001 | 118.6 (89.7, 136.3) | 0.798 | 65.0 (54.0, 84.0) | 0.946 |
| E1 | 96.2 ± 11.4 | 2.02 (1.00, 3.44) | 110.4 (80.5, 145.3) | 66.0 (52.0, 84.3) | ||||
| Segmental sclerosis | ||||||||
| S0 | 91.5 ± 10.2 | 0.003 | 1.06 (0.52, 3.00) | 0.423 | 130.4 (109.3, 144.9) | < 0.001 | 60.3 (51.0, 75.0) | < 0.001 |
| S1 | 96.8 ± 10.8 | 1.50 (0.70, 3.00) | 99.0 (75.2, 125.1) | 68.5 (59.3, 94.0) | ||||
| Tubular atrophy/ interstitial fibrosis | ||||||||
| T0 | 94.9 ± 10.7 | 0.148 | 1.30 (0.64, 3.00) | 0.273 | 118.9 (89.8, 139.4) | 0.001 | 65.0 (54.0, 81.0) | 0.001 |
| T1/T2 | 99.4 ± 7.1 | 2.72 (1.00, 3.43) | 45.3 (18.4, 76.7) | 138.5 (106.8, 276.0) | ||||
| Crescents | ||||||||
| C0 | 93.6 ± 10.7 | 0.75 (0.42, 1.97) | 124.2 (96. 5, 145.6) | 59.1 (50.7, 74.0) | ||||
| C1 | 95.9 ± 11.0 | 1.50 (0.75, 3.05)c | 114.8 (81.9, 134.8)c | 70.2 (54.0, 89.0)c | ||||
| C2 | 95.1 ± 8.8 | 2.49 (1.33, 4.65)cd | 95.9 (41.9, 131.9)c | 68.6 (57.0, 150.5)c | ||||
MAP, mean arterial pressure; Scr, serum creatinine; eGFR, estimated glomerular filtration rate; ISKDC, International Study of Kidney Disease in Children. a P < 0.05 compared with ISKDC-G0, b P < 0.05 compared with ISKDC-G1; c P < 0.05compared with C0, d P < 0.05 compared with C1
Results of MAP were provided in mean ± standard deviation while results of Scr, eGFR, proteinuria were provided in median and (interquartile range)