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. 2019 May 7;12:3491–3507. doi: 10.2147/OTT.S196832

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© 2019 Tang et al.

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INPP4B inhibits EMT in HCC cells. (A) Western blot showing a higher E-cadherin expression and a lower N-cadherin, twist and slug expression in INPP4B overexpression Huh7 and SK-HEP1 cells than that of the corresponding control groups. (B) Western blot analyses of E-cadherin, N-cadherin, twist and slug expression in INPP4B knockdown Huh7/SK-HEP1 cells and the corresponding control cells. (C) Immunofluorescence assays for E-cadherin and N-cadherin expression in INPP4B overexpression Huh7/SK-HEP1 cells and the corresponding control cells. Scale bar, 150 μm.

Abbreviations: INPP4B, inositol polyphosphate 4-phosphatase type II; HCC, hepatocellular carcinoma; EMT, epithelial-to-mesenchymal transition.