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. 2019 May 7;13:1545–1554. doi: 10.2147/DDDT.S196040

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© 2019 Chen et al.

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NLRP3 and caspase-1 expression in three groups by IHC. (A, E and I) control group; (B, F and J) OA group; (C, G and K) GL+OA group. (A–D) NLRP3 and (E–H) caspase-1 staining intensities were strongest in OA group, attenuated in GL+OA group and weakest in control group. *P=0.000 (D), *P=0.000 (H), OA group versus NC group. ^#P=0.013 (D), ^#P=0.000 (H), GL+OA group versus OA group. (I–L) TLR4 staining intensity was not changed obviously in three groups (P=0.277).

Abbreviations: NC, negative control; OA, oleic acid; GL, glibenclamide, IHC, immunohistochemical analyses.