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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Biol Blood Marrow Transplant. 2019 Jan 6;25(5):883–890. doi: 10.1016/j.bbmt.2019.01.003

Table 2.

Monocyte subpopulation recovery (×109/L) post-HCT, by stem cell source, presented as median (inter-quartile range).

Monocyte type BM PBSC SUCB DUCB P-value

N=32 N=75 N=20 N=74
Day 28 AMC 0.63 (0.41–0.96) 0.53 (0.33–0.86) 0.66 (0.48–1.12) 0.51 (0.27–0.83) 0.10
Non-classical 0.03 (0.02–0.05) 0.02 (0.01–0.04) 0.04 (0.02–0.08) 0.03 (0.01–0.07) 0.08
Intermediate 0.08 (0.04–0.14) 0.06 (0.04–0.09) 0.08 (0.06–0.11) 0.08 (0.04–0.16) 0.20
Classical 0.47 (0.24–0.69) 0.38 (0.23–0.60) 0.48 (0.32–0.75) 0.27 (0.16–0.53) 0.02*

N=20 N=59 N=8 N=42

Day 60 AMC 0.40 (0.18–0.68) 0.45 (0.24–0.62) 1.27 (0.59–1.46) 0.95 (0.55–1.27) <0.01*
Non-classical 0.02 (0.01–0.04) 0.03 (0.01–0.04) 0.04 (0.01–0.08) 0.04 (0.02–0.08)  0.05
Intermediate 0.03 (0.02–0.06) 0.04 (0.03–0.06) 0.06 (0.05–0.19) 0.08 (0.05–0.17) <0.01*
Classical 0.30 (0.11–0.49) 0.31 (0.16–0.45) 0.92 (0.48–1.22) 0.70 (0.43–0.96) <0.01*

N=17 N=45 N=9 N=37

Day 100 AMC 0.44 (0.20–0.53) 0.26 (0.17–0.38) 0.9 (0.68–0.95) 0.52 (0.34–0.80) <0.01*
Non-classical 0.01 (0.0–0.05) 0.02 (0.01–0.03) 0.03 (0.01–0.03) 0.02 (0.01–0.05)  0.23
Intermediate 0.04 (0.02–0.06) 0.03 (0.02–0.06) 0.06 (0.05–0.09) 0.07 (0.04–0.10) <0.01*
Classical 0.33 (0.16–0.38) 0.19 (0.10–0.29) 0.69 (0.58–0.78) 0.40 (0.23–0.70) <0.01*

N=16 N=27 N=6 N=32

Day 365 AMC 0.43 (0.30–0.65) 0.48 (0.29–0.68) 0.39 (0.24–0.55) 0.51 (0.33–0.83)  0.58
Non-classical 0.01 (0.01–0.03) 0.02 (0.01–0.04) 0.02 (0.01–0.03) 0.03 (0.01–0.04)  0.24
Intermediate 0.03 (0.02–0.04) 0.03 (0.02–0.08) 0.09 (0.06–0.13) 0.06 (0.04–0.09) <0.01*
Classical 0.33 (0.21–0.52) 0.35 (0.19–0.46) 0.30 (0.17–0.41) 0.41 (0.23–0.64)  0.54

Abbreviations: AMC, absolute monocyte count; BM, bone marrow; DUCB, double umbilical cord blood; HCT, hematopoietic cell transplantation; PBSC, peripheral blood stem cells; SUCB, single umbilical cord blood.

*

P-value < 0.05