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. 2019 May 7;14:3311–3330. doi: 10.2147/IJN.S200847

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© 2019 Liu et al.

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In vivo bioavailability and distribution study. (A) Plasma concentration-time curve of curcumin (CUR) in rats after oral administration of CUR suspensions and CUR/IR780@SMEDDS. (B) Plasma concentration-time curve of IR780 in rats after oral administration of IR780 suspensions and CUR/IR780@SMEDDS. Data are represented as means±SD (n=5). (C) Representative fluorescence images of rats treated with IR780 dispersions and CUR/IR780@SMEDDS at predetermined time points. (D) Representative fluorescence images of isolated tumors and organs, including the gastrointestinal tract.