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. 2019 May 7;14:3311–3330. doi: 10.2147/IJN.S200847

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© 2019 Liu et al.

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In vivo antitumor effects. (A) Photothermal images of 4T1 tumor-bearing nude mice treated with PBS, IR780, and CUR/IR780@SMEDDS under NIR laser irradiation. (B) Tumor temperature-time curve after NIR irradiation (n=3). (C) Photographs of tumors and 4T1 tumor-bearing nude mice treated with control, IR780, CUR, IR780+NIR, CUR/IR780@SMEDDS, CUR@SMEDDS, and CUR/IR780@SMEDDS+NIR 16 days after administration. (D) (a) Tumor volume in nude mice treated with control, IR780, CUR, CUR@SMEDDS, CUR/IR780@SMEDDS, IR780+NIR, and CUR/IR780@SMEDDS+NIR; **p<0.01. (b) Body weight change of tumor-bearing mice. Data are represented as mean±SD (n=7).