Table 2. ROC results of partial DWI and DKI metrics histogram parameters.
| Diagnostic index | AUC | Cutoff value | Se (%) | Sp (%) | PPV (%) | NPV (%) | Accuracy (%) |
|---|---|---|---|---|---|---|---|
| ADC | |||||||
| 50th | 0.64 | 1.455 | 60.0 (24/40) | 72.7 (24/33) | 72.7 (24/33) | 60.0 (24/60) | 65.8 (48/73) |
| Mean | 0.634 | 1.445 | 55.0 (22/40) | 66.7 (22/33) | 66.7 (22/33) | 55.0 (22/40) | 60.3 (44/73) |
| Kurtosis | 0.671 | 2.72 | 84.8 (28/33) | 50.0 (20/40) | 58.3 (28/48) | 80.0 (20/25) | 54.8 (40/73) |
| Dapp 25th | 0.657 | 1.755 | 60.0 (24/40) | 72.7 (24/33) | 72.7 (24/33) | 60.0 (24/60) | 65.8 (48/73) |
| Kapp | |||||||
| 10th | 0.719 | 0.225 | 66.7 (22/33) | 70.0 (28/40) | 64.7 (22/34) | 71.8 (22/39) | 60.3 (44/73) |
| 25th | 0.87 | 0.455 | 66.7 (22/33) | 92.5 (37/40) | 88.0 (22/25) | 77.1 (37/48) | 80.8 (59/73) |
| 50th | 0.881 | 0.655 | 75.8 (25/33) | 85.0 (34/40) | 80.6 (25/31) | 81.0 (34/42) | 80.8 (59/73) |
| 75th | 0.876 | 0.835 | 81.8 (27/33) | 85.0 (34/40) | 81.8 (27/33) | 85.0 (34/40) | 83.6 (61/73) |
| 90th | 0.867 | 0.935 | 87.9 (29/33) | 77.5 (31/40) | 76.3 (29/38) | 88.6 (31/35) | 82.2 (60/73) |
| Mean | 0.889 | 0.625 | 87.9 (29/33) | 80.0 (32/40) | 78.4 (29/37) | 88.9 (32/36) | 83.6 (61/73) |
| SD | 0.771 | 0.345 | 81.8 (27/33) | 65.0 (26/40) | 65.9 (27/41) | 81.2 (26/32) | 72.6 (53/73) |
DWI, diffusion-weighted imaging; DKI, diffusion kurtosis imaging; AUC, area under the curve; Se, sensitivity; Sp, specificity; PPV, highest positive predictive value; NPV, highest negative predictive value; ADC, apparent diffusion coefficient.