Table 3. Diagnostic value of DKI-derived parameters and ADC value in identifying MVI and differentiating the low-grade group (grade I and II) from the high-grade group (grade III and IV).

Group	AUC (95% CI)	Optimal cutoff value	Sensitivity	Specificity	+LR	−LR
Non-MVI group vs. MVI group
MK	0.77 (0.66–0.86)	≥0.86	68.4% (51.3–82.5%)	75.0% (57.8–87.9%)	2.74	0.42
Low-grade HCC vs. high-grade HCC
ADC	0.74 (0.63–0.84)	≤1.25	75.9% (56.5–89.7%)	60.0% (44.3–74.3%)	1.90	0.40
MD	0.76 (0.65–0.85)	≤1.46	86.2% (68.3–96.1%)	60.0% (44.3–74.3%)	2.16	0.23
MK	0.81 (0.70–0.89)	≥0.89	72.4% (52.8–87.3%)	82.2% (67.9–92.0%)	4.07	0.34

ADC, apparent diffusion coefficient; CI, confidence interval; LR, likelihood ratio; MD, mean corrected apparent diffusion coefficient; MK, mean apparent kurtosis coefficient; DKI, diffusion kurtosis imaging.