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. 2019 Apr;9(4):681–690. doi: 10.21037/qims.2019.04.11

Table 4. Diagnostic performances of the mean homogeneity indices obtained from 12 ROIs for discriminating Warthin tumor from normal parotid parenchyma.

ROI size (mm2) Optimal cutoff values AUC ± SE (95% CI) Sensitivities (95% CI) Specificities (95% CI) PPV (%) NPV (%) ACC (%)
9 0.09 0.723±0.056 (0.620–0.811) 55.6 (38.1–72.1) 82.1 (69.6–91.1) 66.6 74.2 71.7
28 0.15 0.784±0.049 (0.686–0.863) 66.7 (49.0–81.4) 78.6 (65.6–88.4) 66.7 78.6 73.9
34 0.17 0.793±0.048 (0.696–0.870) 80.1 (64.0–91.8) 71.4 (57.8–82.7) 64.3 84.8 74.8
50 0.19 0.793±0.047 (0.696–0.871) 86.1 (70.5–95.3) 60.7 (46.8–73.5) 58.5 87.2 70.6
60 0.17 0.790±0.048 (0.693–0.868) 72.2 (54.8–85.8) 73.2 (59.7–84.2) 63.4 80.4 72.8
82 0.18 0.776±0.051 (0.677–0.857) 75.0 (57.8–87.9) 73.2 (59.7–84.2) 64.3 82.0 73.9
93 0.19 0.777±0.051 (0.679–0.857) 72.2 (54.8–85.8) 75.0 (61.6–85.6) 65.0 80.8 73.9
98 0.19 0.779±0.052 (0.681–0.859) 75.0 (57.8–87.9) 75.0 (61.6–85.6) 65.9 82.4 75.0
115 0.19 0.774±0.053 (0.675–0.855) 72.2 (54.8–85.8) 78.6 (65.6–88.4) 68.4 81.5 76.1
130 0.18 0.773±0.054 (0.674–0.854) 61.1 (43.5–76.9) 87.5 (75.9–94.8) 75.9 77.8 77.2
136 0.20 0.765±0.055 (0.665–0.847) 66.7 (49.0–81.4) 83.4 (67.6–89.8) 72.1 79.6 76.9
149 0.17 0.752±0.057 (0.652–0.837) 55.6 (38.1–72.1) 94.6 (85.1–98.9) 86.9 76.8 79.3

ROC, receiver operating characteristic curve; AUC, area under curve; ADC, apparent diffusion coefficient; SE, standard error; CI, confidence interval; ROI, region of interest; PPV, positive predictive value; NPV, negative predictive value; ACC, accuracy.