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. 2019 Apr;9(4):681–690. doi: 10.21037/qims.2019.04.11

Table 5. Diagnostic performances of the mean homogeneity indices obtained from the 12 ROIs for discriminating pleomorphic adenomas from Warthin tumor.

ROI size (mm2) Optimal cutoff values AUC ± SE (95% CI) Sensitivities (95% CI) Specificities (95% CI) PPV (%) NPV (%) ACC (%)
9 0.07 0.731±0.061 (0.615–0.828) 63.9 (46.2–79.2) 83.8 (68.0–93.8) 79.3 70.5 74.0
28 0.10 0.742±0.059 (0.627–0.838) 63.9 (46.2–79.2) 83.8 (68.0–93.8) 79.3 70.5 74.0
34 0.11 0.746±0.059 (0.631–0.841) 63.9 (46.2–79.2) 83.8 (68.0–93.8) 79.3 70.5 74.0
50 0.12 0.740±0.059 (0.624–0.836) 61.1 (43.5–76.9) 91.1 (68.0–93.8) 87.0 70.6 76.3
60 0.12 0.735±0.059 (0.619–0.831) 61.1 (43.5–76.9) 81.1 (64.8–92.0) 75.9 68.2 71.2
82 0.14 0.734±0.059 (0.618–0.831) 61.1 (43.5–76.9) 81.1 (64.8–92.0) 75.9 68.2 71.2
93 0.14 0.730±0.059 (0.614–0.828) 55.6 (38.1–72.1) 83.8 (68.0–93.8) 77.0 66.0 69.9
98 0.14 0.734±0.059 (0.618–0.831) 61.1 (43.5–76.9) 78.4 (61.8–90.2) 73.3 67.4 69.9
115 0.17 0.738±0.058 (0.622–0.834) 50.0 (32.9–67.1) 89.2 (74.6–97.0) 81.8 64.7 69.9
130 0.12 0.734±0.059 (0.618–0.831) 80.1 (64.0–91.8) 56.8 (39.5–72.9) 64.3 74.6 68.3
136 0.12 0.742±0.058 (0.627–0.838) 77.8 (60.8–89.9) 62.2 (44.8–77.5) 66.7 74.2 69.9
149 0.12 0.749±0.058 (0.634–0.843) 86.1 (70.5–95.3) 59.5 (42.1–75.2 67.4 81.5 72.6

ROC, receiver operating characteristic curve; AUC, area under curve; ADC, apparent diffusion coefficient; SE, standard error; CI, confidence interval; ROI, region of interest; PPV, positive predictive value; NPV, negative predictive value; ACC, accuracy.