Table 2. Differences in the short-range FCD, long-range FCD, and gray matter volume between the PACG and HC groups.
| Brain regions | Cluster size (voxels) | BA | MNI coordinates | Peak T values | ES | ||
|---|---|---|---|---|---|---|---|
| x | y | z | |||||
| Increased short-range FCD | |||||||
| Left PHG/INS/IFG | 428 | 30/47/34 | −27 | 9 | −21 | 4.29 | −0.34 |
| Right INS/IFG | 441 | 44/45/13 | 48 | 18 | 6 | 4.80 | 0.43 |
| Decreased short-range FCD | |||||||
| Occipital/cuneus/preCUN/SPL/PCL | 1,480 | 18/19/7 | 21 | −90 | 18 | −5.38 | 0.51 |
| Decreased long-range FCD | |||||||
| Left MFG | 155 | 10 | −30 | 39 | 27 | −4.86 | -0.35 |
Negative T value means the resting-state FCD in PACG is smaller than HC. Positive ES means the resting-state FCD in HC is larger than PACG. FCD, functional connectivity density; PACG, primary angle-closure glaucoma; HC, healthy control; BA, Brodmann area; MNI, Montreal Neurological Institute; ES, effect size; IFG, inferior frontal gyrus; PHG, parahippocampal gyrus; INS, insula; preCUN, precuneus; SPL, superior parietal lobe; PCL, Postcentral Lobe; MFG, middle frontal gyrus.