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Overexpression of miR-186-5p or down-regulation of Eg5 in neuroblastoma cell lines could induce G1 cell cycle arrest. A: Cell cycle was detected by flow cytometry; B: Cell cycle distribution of SHSY-5Y cells in different groups; C: Cell cycle distribution of Kelly cells in different groups. miR-186-5p overexpression or down-regulation of Eg5 in SHSY-5Y and Kelly cell lines could increase the number of G1 phase cells and decrease the number of S phase and G2/M phase cells.
