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Activation of the PI3K/AKT/mTOR pathway reversed the effect of euscaphic acid on cell cycle and apoptosis. A. The effect of euscaphic acid supplemented with IGF-1 on the cell cycle arrest of CNE-1 and C666-1 cells as detected by flow cytometry. B. The effect of euscaphic acid supplemented with IGF-1 on apoptosis in CNE-1 and C666-1 cells was detected by flow cytometry. ***P<0.001.
