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. 2019 May 2;13:383. doi: 10.3389/fnins.2019.00383

FIGURE 3.

FIGURE 3

Glutamatergic synapse: Effects of maternal and offspring genotypes, diet, sex and behavioral phenotype on the cerebral cortex. (A) Examples of GluR1 and GluR2 blots. GluR1/GluR2 and NR2A/NR2B ratios presented by behavioral categories in males (B,C) and females (D,E). N, Male, Wt-Wt-CD, 8; Non-Symptomatic, 16, Symptomatic, 8. Female, Wt-Wt-CD, 11; Non-Symptomatic, 27; Symptomatic, 8. Protein levels of the glutamatergic synapse normalized to beta-actin levels (except where indicated otherwise) in male (F) and female (G) experimental groups. N, male, Wt-Wt-CD, 8; Wt-Het-CD, 5; Het-Het-CD, 7; Het-Het-PP, 6; female, Wt-Wt-CD, 9; Wt-Het-CD, 7; Het-Het-CD, 9; Het-Het-PP, 9, Het-Het-PN, 6. P-value in the figure refers to the difference obtained by a one-way ANOVA post hoc test compared to the Wt-Wt-CD group. Additional values are as follows for (F): GluR1/GluR2 Het-Wt-CD vs. Het-Het-CD 0.04, and Het-Wt-CD vs. Het-Het-PP 0.004. In all other post hoc tests, significant differences were found only when compared to the Wt-Wt-CD group, as indicated in the figure. Data are presented as mean ± SEM.