Figure 5.
Summary of SAR results for compounds 8–17. Compound 7 bound to the active site of MtbAdoK. Based on the MtbAdoK-7 complex, compounds 8–17 where synthesized. Chain A is colored white, and chain B is colored magenta.
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.