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. 2019 Apr 5;10(5):792–799. doi: 10.1021/acsmedchemlett.9b00050

Table 2. EC50 Values and Emax (Arrestin-TANGO) of Selected D1R Agonists.

  arrestin-TANGO
compd EC50a (nM) Emax (% DA)a
1 1400 ± 190 100
2 360 ± 70 76 ± 6
5 490 ± 100 45 ± 4
6 320 ± 50 21 ± 2
7 1100 ± 300 9 ± 2
19 35 ± 4 86 ± 14
24 NAb NAb
a

The values are the mean ± SEM of at least three independent experiments.

b

NA = no activity.